Intermediates Isotretinoin Antibiotics Hmoov

Cov lus txhais: 13-cis-ra; 13-cis-retinoicaci; 13-sm;; Isoretinoin; isotrex; neovitaminaacid; ro-4-3780
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0
Tsham tam sim no
Txhawb tshuaj

Intermediates Isotretinoin CAS 4759-48-2 Antibiotics Raw Materials

Khoom Npe: Isotretinoin
Cov lus txhais: 13-cis-ra; 13-cis-retinoicaci; 13-sm;; Isoretinoin; isotrex; neovitaminaacid; ro-4-3780
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0


Isotretinoin Lub mechanism yog raws li nram no:

① nws tuaj yeem txo cov qog qhov hnyuv thiab ua rau tsis zoo rau cov qog qhov quav, txo cov nyhuv ntawm qhov qog sebaceous qog, yog li inhibiting qhov kev loj hlob ntawm Propionibacterium uas ua rau thaj chaw lipid.
② nws muaj ib qho kev cuam tshuam txog kev tiv thaiv kev ua kom tsis muaj zog, tuaj yeem tiv thaiv qhov tshaj tawm ntawm epidermal thiab txhawb nws qhov txawv. Nws kuj txo cov keratosis ntawm cov hauv paus plaub hau thiab catheter ntawm sebaceous qog.
③ nws tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lymphocytes thiab monocytes, thiab inhibit chemotaxis ntawm neutrophil, thiab yog li muaj kev cuam tshuam kev ua haujlwm.
④ nws muaj peev xwm nrhav nws cov nyhuv kho los ntawm kev xaiv losis kev sib tw ntawm Vitamin A kua txauj rau nuclear. Nws muaj peev xwm inhibit qhov proliferation ntawm pob txuv pas bacilli. Tshaj ntawd nws muaj cov teebmeem ntawm kev tiv thaiv kev tiv thaiv ntawm qis tshuaj, tab sis muaj kev tiv thaiv kev pib ntawm kev siab tshaj.
Nws muaj peev xwm inhibit biogenesis ntawm collagenase thiab gelatinase nyob rau hauv daim tawv nqaij, thiab tseem muaj peev xwm inhibit kev ua si ntawm ornithine decarboxylase. Rov qab rau lub luag hauj lwm loj ntawm ornithine decarboxylase hauv inducing ntawm daim tawv nqaij hloov, ces yogotretinoin kuj suppress tumorigenesis.
⑥ thaum cov teeb meem tshuaj pleev kom tswj, nws muaj cov tswv yim zoo xws li cov tshuaj vitamin A acid uas tsim kev loj hlob ntawm epidermal cell, txhawb nqa qhov txawv ntawm epidermal cell granular txheej rau hauv stratum corneum. Nws tseem yuav tswj cov horny ntsaws tshwm sim thaum lub sij hawm qee qhov txawv txav cornification kev ntawm plaub hau follicles sebaceous epithelium, thiab yog li ua si ib lub luag hauj lwm kho.


Isotretinoin Chem Tshuaj:

Nws yog xim txiv kab ntxwv cov xim daj uas tau los ntawm isopropanol, melting point 174 ~ 175 ° C. UV Maximum absorption: 354nm (θ39800). Mob toxicity LD50 (20 hnub) nas, nas (mg / kg): 904,901 intraperitoneal txhaj; 3389> 4000 qhov ncauj hais lus.
Siv Vitamin A tshuaj yeeb tshuaj. Nws muaj peev xwm sai thiab ntseeg tau kom tsis txhob muaj ntau lub xov tooj ntawm tes thiab sib txawv ntawm cov qog ntawm qog hlwb. Nws muaj cov nyhuv siab rau cov mob nodular cystic acne. Cov khoom noj no muaj lub plab hnyuv siab, tab sis tsis ua haujlwm rau kev tswj hwm pleev tshuaj. Nws siv rau kev kho mob hnyav heev uas tsis tuaj yeem raug kho los ntawm lwm cov tshuaj. Nws kuj muaj qee cov teebmeem txog kev kho pob txuv, pobtxha, pobtxha, mob qog nqaij hlav, thiab lwm yam kabmob liab.
Cov Khoom Siv Tshuaj Daj Daj-Txiv Kab Ntxwv Crystalline Hmoov
Siv 5HT1a receptor agonist, txhawj xeeb
Siv Siv los ua kev kho mob rau pob txuv. Sij hawm tseem tab tom kawm txog kev kho mob ntawm tawv nqaij.


Synephrine

Prilocaine

Orlistat

Benzocaine

Pregabalin

Lidocaine / Xylocaine

Methylamine hydrochloride

Tetracaine

gamma-Butyrolactone / GBL

Txheej txheem

Isotretinoin

Propitocaine hydrochloride

Phenacetin

Tetracaine hydrochloride

Benzyl benzoate

Procaine hydrochloride

Benzyl cawv

Pramoxine hydrochloride

Ethyl Oleate

Proparacaine hydrochloride

4-Acetamidophenol / Paracetamol

Benzoroine hydrochloride

Guaiacol

Lidocaine hydrochloride

Tranexamic acid / Amstat

Articaine hydrochloride

Tetracycline hydrochloride

Levobupivacaine hydrochloride

Griseofulvin

Ropivacaine hydrochloride

Triclosan

Dibucaine hydrochloride

Ibuprofen

Bupivacaine hydrochloride

Aniracetam

Oxiracetam

Captopril

Pramiracetam

Piracetam

Noopept


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